Ben Medrano, MD
Understanding Trauma: A Journey Through the Brain and Beyond
Trauma is a profound psychological and neurobiological experience that changes how our brains process emotions, form memories, and interact with the world around us.
According to a World Health Organization (WHO) report, approximately 70% of people worldwide will encounter a potentially traumatic event during their lives. For some, these experiences leave lasting impressions that can make daily life challenging.
While traditional treatments like Cognitive Behavioral Therapy (CBT) and SSRI medications help many people find relief, many trauma survivors don't get better with these approaches. This treatment gap has sparked fascinating research into new options, including psychedelic therapy for trauma.
Why Is Trauma So Tricky to Treat?
Trauma literally changes how our brains file away memories. Normal memories get neatly organized in the hippocampus but traumatic memories become fragmented and get primarily stored through the amygdala, creating what scientists call a hyperactive "fear network".
This unique brain response creates several challenges. Talk therapy often hits a wall because traumatic memories aren't stored in brain regions easily accessed through talking.
In fact, sometimes talking about trauma can accidentally reinforce those neural pathways associated with the traumatic experience—similar to repeatedly walking the same path through a forest, making the trail more pronounced over time.
Medication typically offers temporary relief. SSRIs often provide symptom management while you're taking them, but many people experience relapse after stopping—comparable to using temporary protection during bad weather rather than addressing the underlying structural issues.
Additionally, treatment resistance is common. Other roadblocks include avoidance behaviors (the brain's natural attempt to protect itself), difficulty putting traumatic experiences into words, high dropout rates from traditional therapies, and overlapping mental health conditions.
Psychedelic Therapy: A Different Path Through Trauma
Psychedelic therapy for trauma offers something truly unique—it uses different neurobiological mechanisms to access and process traumatic memories in new ways.
MDMA: Creating a Safe Space in Your Mind
MDMA (sometimes called "ecstasy" outside medical settings) creates an ideal inner environment for trauma processing. It turns down amygdala activity (reducing fear) while boosting prefrontal cortex activity (enhancing clear thinking).
The medicine releases a cocktail of helpful brain chemicals—serotonin, dopamine, norepinephrine, and oxytocin—promoting trust and emotional openness. More than two-thirds of participants receiving MDMA-assisted psychotherapy no longer met PTSD criteria after 18 weeks, compared to about one-third in the placebo group.
Psilocybin: Rewiring Your Brain's Highways
Psilocybin (the active compound in "magic mushrooms") works like a temporary neural reset button. It quiets the default mode network—the brain system responsible for your inner chatter and self-criticism.
Studies show it promotes increased neural resilience and new connections—essentially helping your brain form new pathways that bypass trauma-established patterns. This allows you to see your experiences from new perspectives, often with profound insight.
Ketamine: Quick Relief and Brain Renovation
Ketamine offers some unique advantages in trauma treatment. Unlike most antidepressants, it provides fast-acting symptom relief, often within hours instead of weeks. Research indicates improved memory reconsolidation—helping rewrite traumatic memories as they're recalled.
The Magic Ingredient: The Therapeutic Container
The effectiveness of psychedelic therapy isn't just about the medicine. It's about the supportive framework surrounding it. This framework includes thorough preparation (building trust and setting meaningful intentions), guided sessions with therapist support during your experience, and expert-guided integration to make sense of insights and bring them into everyday life.
Your Psychedelic Therapy Journey: What to Expect
Psychedelic therapy typically begins with a thorough initial assessment reviewing your medical history and mental health to ensure this approach is right for you, along with providing informed consent in therapy to address safety and ethical considerations.
This is followed by preparation sessions where you build a relationship with your therapist and set intentions for healing. The medicine session itself provides an opportunity to experience an altered state of consciousness that creates psychological flexibility. After the session, integration work with your therapist helps interpret insights and develop strategies to apply them in daily life.
This process can be carried out through at-home psychedelic therapy, offering accessibility and personalized guidance.
Everyone's Healing Path Looks Different
Just as no two people experience trauma in exactly the same way, healing journeys are equally unique. Some find relief through traditional therapies, while others experience breakthroughs with psychedelic therapy for trauma.
Psychedelic approaches show particular promise for those who haven't responded to conventional methods.
Many find that combining complementary approaches, such as EMDR therapy for PTSD, creates the most effective healing journey. Ketamine-assisted therapy can support your unique healing process with comprehensive care addressing both symptoms and underlying trauma patterns.
Transform Your Trauma Recovery with Psychedelic-Assisted Therapy
Traumatic experiences reshape the brain, creating patterns that traditional therapies can't always reach. Psychedelic medicines like ketamine, MDMA, and psilocybin work differently—creating neurological flexibility that allows you to process trauma from new perspectives while supported by experienced guides.
Whether you've struggled with treatment-resistant PTSD or are exploring options beyond conventional therapy, Innerwell's affordable ketamine therapy provides a scientifically-backed approach to trauma healing.
Our comprehensive program combines the neurobiological benefits of ketamine with expert therapeutic support—from preparation through integration—ensuring you're supported at every step of your healing journey.
Your path to transformation doesn't have to be walked alone. Schedule a consultation today to discover how ketamine-assisted therapy might fit into your unique healing process. Our experienced clinicians specialize in trauma treatment and can help determine if this innovative approach is right for you.