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What to know if you’re nervous about your first Ketamine experience

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What to know if you’re nervous about your first Ketamine experience

  • Written by

    Ben Medrano, MD


Embarking on your first ketamine session can be both exciting and nerve-wracking. It's perfectly normal to feel a mix of emotions before this unique journey. To ease any concerns, let's explore what you need to know about your first ketamine experience.

Understanding the Safety of Ketamine:

Ketamine has a longstanding track record of safety, having been administered to millions of adults and children since 1970. Notably, it differs from opioids and benzodiazepines in that it does not pose respiratory issues, even in higher doses.

Over the past three decades, extensive studies have investigated ketamine's efficacy in treating depression, anxiety, and PTSD. The findings consistently affirm its safety and effectiveness in addressing these conditions.

Starting Slow and Tailoring to You:

Your journey with ketamine begins at a low dose, allowing you to acclimate to its effects. At this level, ketamine induces a deep sense of relaxation, akin to enjoying a glass of wine. As your sessions progress, doses can be adjusted to align with your unique circumstances, condition, and treatment goals. Higher doses often manifest as dream-like experiences, where intricate imagery and altered self-perception may arise.

Potential Side Effects:

While most patients experience no side effects, those who do typically encounter brief and minimal issues lasting 1 to 2 hours. Common side effects include nausea, dizziness, headache, grogginess, and blurry vision.

Addressing First-Time Nerves:

Feeling nervous about your inaugural ketamine session is entirely normal. To help ease any apprehensions, adopt the mantra from Johns Hopkins Center for Psychedelic & Consciousness Research: Trust, Let Go, and Be Open (TLO).

  1. Trust in the Process: You've been prescribed a legitimate, safe, and effective medicine tailored to your mental health needs. Your session will take place in a secure and comfortable setting, with a support person present to assist you. The experience is time-limited, lasting just one hour. Any anxiety or challenges during the session will be transient, leaving you with newfound insights.
  2. Let Go of Preconceived Notions: Release any fears or preconceived notions about the experience. Trust that the medicine will guide you toward the healing experience you need.
  3. Be Open: Keep in mind the intentions you've set for the session and your treatment goals. Simultaneously, be open to observing aspects of yourself and your life that the medicine may reveal.

As you step into this transformative experience, remember that you are in capable hands, supported by a reputable medical team. Your journey with ketamine holds the potential for profound healing and self-discovery. Trust the process, let go of any apprehensions, and be open to the transformative power of this innovative treatment.

If you have any questions or need further guidance, our team at Innerwell is here to support you. Your well-being is our priority, and we look forward to assisting you on your path to mental health recovery.

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